Renal papillary necrosis in sickle-cell haemoglobinopathy.
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چکیده
منابع مشابه
Renal papillary necrosis in a patient with sickle cell trait.
A patient with sickle cell trait who presented with gross hematuria and was subsequently found to have renal papillary necrosis is presented. The hematuria resolved with conservative therapy consisting of bed rest and hydration with hypotonic intravenous fluids. The pathophysiology of renal abnormalities associated with sickle cell trait is described. The management of the primary clinical mani...
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We describe a case of renal papillary necrosis in a middle-aged female with sickle cell trait who presented with gross hematuria. We wish to highlight this case for several reasons. Sickle cell trait is often viewed as a benign condition despite the fact that it is associated with significant morbidity such as renal papillary necrosis and renal medullary carcinoma. Appropriate evaluation needs ...
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Sickle cell trait is a benign haemoglobin disorder which rarely results in disease or complications. A few cases of osteonecrosis have been reported in the literature in parts of the world with advanced health care system. There are various predispositions to developing avascular necrosis in general, while the sickle beta globin gene inheritance is the most efficient factor. Injection drug abus...
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Background: Until now, trimodal distribution of HbS has been seen by six different studies in the world when associated with alpha-thalassemia with confirmation by corresponding alpha-genotyping studies. The RBC indices reduce as alpha-globin genes reduce in sickle cell trait (SCT) patients, which decreases the extent of intra-vascular sickling and thus betters the clinical cou...
متن کاملRenal papillary necrosis in a patient with sickle cell disease
enal manifestations in sickle cell disease (SCD) occur in onehird of adolescents and young adults.1 These manifestations ccur because the kidney is sensitive to hypoxia-induced vasocclusion resulting from the adhesion of sickled red blood cells o the endothelium.2,3 The renal medulla is characterized by cidosis, hypertension, and hypoxia. These factors promote he polymerization and sickling of ...
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عنوان ژورنال:
- British medical journal
دوره 3 5560 شماره
صفحات -
تاریخ انتشار 1967